The Giants will need to make at least two changes for Friday night's massive clash with the Western Bulldogs at Etihad Stadium. 

Dawson Simpson will be selected to replace the suspended Shane Mumford, and will come into the side in terrific form, having had 21 possessions and 10 tackles to go with 70 hit-outs in the NEAFL last week.

Mumford's loss will be offset by the return of club champion Toby Greene, who has served his two-week ban, while Jonathan Patton could also add firepower to the GWS forward line.

Patton was a late withdrawal from last week's win over Melbourne with hamstring tightness and could be selected if he can train during the week.

After such an outstanding win over the Demons it's unlikely coach Leon Cameron will be making too many other changes, but Daniel Lloyd and Tendai Mzungu would come under serious consideration if he does, after they combined for 75 touches and 16 tackles in the reserves' narrow loss to the Canberra Demons last week.